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ML0019

Amylin, human
KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY (C2&C7 bridge)
Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Ala-Ile-Leu-Ser-Ser-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr(Cys2&Cys7 bridge)
Description:37 amino acid polypeptide secreted from the b cells of the pancreas and structurally related to calcitonin. It has anorectic effects in rats and may be responsible for the etiology of insulin resistance of type II diabetes mellitus through its modulation of peripheral effects of insulin. It blocks the activation of glycogen synthase by insulin.
 

 

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